翻訳と辞書 Words near each other ・ Ventricose ・ Ventricular action potential ・ Ventricular aneurysm ・ Ventricular assist device ・ Ventricular dysphonia ・ Ventricular dyssynchrony ・ Ventricular escape beat ・ Ventricular fibrillation ・ Ventricular flutter ・ Ventricular hypertrophy ・ Ventricular inversion ・ Ventricular outflow tract ・ Ventricular outflow tract obstruction ・ Ventricular pressure ・ Ventricular reduction ・ Ventricular remodeling ・ Ventricular septal defect ・ Ventricular system ・ Ventricular tachycardia ・ Ventricular-brain ratio ・ Ventricularia ・ Ventriculitis ・ Ventriculography ・ Ventriculomegaly ・ Ventriculostomy ・ Ventriculotomy ・ Ventriculotomy (cardiac) ・ Ventriculus ・ Ventridens ・ Ventrifossa Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Ventricular remodeling ： ウィキペディア英語版 Ventricular remodeling Ventricular remodeling (or cardiac remodeling) refers to the changes in size, shape, structure and physiology of the heart after injury to the myocardium. The injury is typically due to acute myocardial infarction (usually transmural or ST segment elevation infarction), but may be from a number of causes that result in increased pressure or volume overload (forms of strain) on the heart. Chronic hypertension, congenital heart disease with intracardiac shunting, and valvular heart disease may also lead to remodeling. After the insult occurs, a series of histopathological and structural changes occur in the left ventricular myocardium that lead to progressive decline in left ventricular performance. Ultimately, ventricular remodeling may result in diminished contractile (systolic) function and reduced stroke volume. Medically speaking, "ventricular remodeling" implies a decline in function (even though the word "remodeling" usually implies improvement). Remodeling of the ventricles under left/right pressure demand make mismatches inevitable. Pathologic pressure mismatches between the pulmonary and brain/systemic circulation guide compensatory remodeling of the left and right ventricles. The term "reverse remodeling" in cardiology implies an improvement in ventricular mechanics and function following a remote injury or pathologic process. Concentric hypertrophy is due to pressure overload, while eccentric hypertrophy is due to volume overload. ==Pathophysiology== The cardiac myocyte is the major cell involved in remodeling. Fibroblasts, collagen, the interstitium, and the coronary vessels to a lesser extent, also play a role. A common scenario for remodeling is after myocardial infarction. There is myocardial necrosis (cell death) and disproportionate thinning of the heart. This thin, weakened area is unable to withstand the pressure and volume load on the heart in the same manner as the other healthy tissue. As a result, there is dilatation of the chamber arising from the infarct region. The initial remodeling phase after a myocardial infarction results in repair of the necrotic area and myocardial scarring that may, to some extent, be considered beneficial since there is an improvement in or maintenance of LV function and cardiac output. Over time, however, as the heart undergoes ongoing remodeling, it becomes less elliptical and more spherical. Ventricular mass and volume increase, which together adversely affect cardiac function. Eventually, diastolic function, or the heart's ability to relax between contractions may become impaired, further causing decline. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Ventricular remodeling」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.